Model Calibration with Scientific Python.
TreeAge Pro models can be calibrated using Scientific Python (SciPy) libraries. An example of a calibration of a Markov 3 state progression model with Weibull transition hazards using Nelder-Mead optimization algorithm can be found by following this link. The compressed archive includes instructions for installing Python, as well as overview of the calibration process, TreeAge Pro model and working Python script. There is also a video showing the sample calibration session.
A research poster detailing results obtained by using different optimization algorithms was presented at ISPOR conference in Tokyo on September 11, 2018. The poster is available by following this link.