38.10 Three-State PartSA Model

PartSA models are not limited to two Survival Curve nodes. Your model could have three or more Survival Curve nodes. The Partitioned Survival Analysis Example Model PartSA-3State.trex is show below.

The three Survival Curve nodes each represent a living state, along with the implicit Dead state. The Survival Curve graph from this model is presented below.

Note that you could use a three state model to handle a situation where treatment for the Progression-Free state may continue beyond actual membership in that state. The middle curve could use the cost for the Progression-Free state, but the utility for the Post-Progression state. Potentially, the cost calculations for continuation of treatment could be some combination of PFS and PPS costs.