Understand & Use Your Clinical Data
TreeAge Pro helps you explore and interpret clinical evidence, understand how risk changes over time, and translate that evidence into your model.
Source data can take many forms – Kaplan-Meier curves or tables, patient-level data, fitted distributions, published probabilities, hazard ratios, treatment effects, etc. Understanding what the evidence tells you is an important first step in building a defensible model.
TreeAge Pro provides tools to visualize and interpret clinical evidence, explore alternative representations, and use that evidence to drive disease progression within your model.
Kaplan-Meier Survival Data
Consider a common example – Kaplan-Meier Survival Data.
Kaplan-Meier data provides critical evidence about observed survival, but modelers often need to determine how that evidence should be represented—and how outcomes should be projected beyond the observed period—before using it to drive a model.
TreeAge Pro provides key tools for transforming that data, so it can be used in your model. TreeAge Pro can also use input data from regression analysis tools that you may prefer for fitting your data.
Survival to Hazard Converter
This tool converts the original survival table data to a hazard table representing changing risk over time.
The resulting hazard data can then be used to drive disease progression in your model.
Fit Distribution to a Survival Table
TreeAge Pro’s curve-fitting algorithm matches the survival data to a distribution.
The fitted distribution can then drive disease progression in your model.
Use Fitted Distributions from Regression Analysis
You might choose to use statistical regression analysis with SAS, Stata or R to fit distributions to your clinical data.
TreeAge Pro can help you visualize the fits of those distributions as well as the impact of extrapolation beyond the observed period.
