Markov Model Software

Add health states and events: Add health states within the TreeAge Pro Markov framework directly to the right of the Markov node. Add events to the right of each health state to create patient pathways for each Markov cycle. Each patient pathway automatically ends with a referral back to a health state to start the next Markov cycle.

Enter event probabilities: Enter event probabilities directly under each event within the Markov framework. The probabilities can change over time. As patients experience the events over time, the overall cohort is split among the states and events differently as time passes. In a Markov Simulation Model, you can vary probabilities based on individual patient characteristics and/or patient history.

Enter costs and utilities: Add costs and/or utilities at any health state or event.  Costs and utility entries are automatically accumulated as patients pass through the model in each Markov cycle.

TreeAge Pro takes care of the calculations: Your health states, events, probabilities, costs and utilities are seamlessly integrated into model calculations.

As patients move through the states and events, costs and utilities are accumulated based on the percentage of the overall cohort that passed through that specific node in the model. The overall weighted average of cost/utility from every health state and event in every cycle results in the average cost and utility per patient. Markov Cohort Reports provide cycle-by-cycle details on disease progression cohort flow and the accumulation of cost and utility. Built-in functions handle half-cycle correction and discounting within the Markov process.